Scientific Papers

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Scientific Papers 10 December 2021

An Evolutionary Portrait of the Progenitor SARS-CoV-2 and Its Dominant Offshoots in COVID-19 Pandemic

Abstract Global sequencing of genomes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has continued to reveal new genetic variants that are the key to

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pre-print 28 November 2021

Pre-existing humoral immunity to human common cold coronaviruses negatively impacts the protective SARS-CoV-2 antibody response

* Human common cold CoV (hCCCoV) antibodies before and after SARS-CoV-2 infection was assessed * Betacoronavirus hCCCoV antibodies are boosted after SARS-CoV-2 infection * Baseline hCCCoV antibodies do

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Scientific Papers 24 May 2021

NEWS2 Score is more accurate than COVID-GRAM for prediction of Critical illness

Abstract PURPOSE: Clinical scores to rapidly assess the severity illness of Coronavirus Disease 2019 (COVID-19) could be considered of help for clinicians. Recently, a specific

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Scientific Papers 8 May 2020

Innate Immunity against COVID-19

An article published in the Physiological Genomics [https://journals.physiology.org/doi/full/10.1152/physiolgenomics.00033.2020] (American physiological society) suggests immunomodulation through activation

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Scientific Papers 5 May 2020

A human monoclonal antibody blocks SARS-CoV-2 in cell culture

An article published in Nature Communications [https://www.nature.com/articles/s41467-020-16256-y] reports a recombinantly expressed human chimeric 47D11 H2L2 antibody, reformatted to a fully

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Scientific Papers 3 May 2020

Potential use of hydroxychloroquine, ivermectin and azithromycin drugs in fighting COVID-19: trends, scope and relevance

Mini-Review published [https://www.sciencedirect.com/science/article/pii/S2052297520300366#bib14] in New Microbes and New Infections [https://www.sciencedirect.com/science/journal/20522975] journal

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Scientific Papers 2 May 2020

Temperature and humidity decreases daily new cases and new deaths of COVID-19

Pre-print published [https://www.ncbi.nlm.nih.gov/pubmed/32361460]in the science of the total environment journal [https://www.journals.elsevier.com/science-of-the-total-environment](Elsevier

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Scientific Papers 27 April 2020

Entry points of SARS-CoV-2 mapped in study

A website 'https://www.covid19cellatlas.org/' provides comprehensive mapping of potential cellular entry of coronaviruses, especially the SARS-CoV-2, which has affinity for the nasal

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Scientific Papers 24 April 2020

Chest CT Findings in COVID-19

A study published in Radiology: Cardiothoracic Imaging [https://pubs.rsna.org/doi/10.1148/ryct.2020200110] evaluated the chest CT findings of 104 cases with

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Scientific Papers 23 April 2020

Viral dynamics across a spectrum of disease severity in COVID-19

A Letter to the Editor published in the Journal of Infection [https://www.journalofinfection.com/article/S0163-4453(20)30225-5/pdf] reports the "findings of a

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Scientific Papers 21 April 2020

Presentation & Outcomes Report from 5.7k patients of NYC

A study published in the JAMA [https://jamanetwork.com/journals/jama/fullarticle/2765184]reported the characteristics, clinical presentation and outcomes of patients hospitalised with COVID-19

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Scientific Papers 16 April 2020

Type 1 interferons as a potential treatment against COVID-19

In a review published in the NEJM [https://www.sciencedirect.com/science/article/pii/S0166354220302059], 'preliminary data concerning the potential activity of type 1 interferons

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Scientific Papers 15 April 2020

Ventilation as critical as social distancing and hand washing, etc

A paper published in NEJM [https://www.sciencedirect.com/science/article/pii/S016041202031254X] advices ventilation as one of the means of removal of virus-laden droplets

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Scientific Papers 15 April 2020

Remdesivir is a high potent direct-acting antiviral that inhibits SARS-CoV-2

A scientific paper published in Journal of Biological Chemistry informs that inhibition of RNA-dependent RNA polymerase (RdRp) required for SARS-CoV-2's replication in the infected cells

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Scientific Papers 14 April 2020

SARS-CoV-2 infects T lymphocytes thro Spike protein

A paper published in NATURE [https://www.nature.com/articles/s41423-020-0424-9] reports that the SARS-CoV-2 virus could infect T cells through receptor-dependent, S protein-mediated membrane