Visualisations 12 April 2020 Genomic epidemiology of SARS-CoV-2 A visually rich and animated phylogeny [https://nextstrain.org/ncov] shows evolutionary relationships of hCoV-19 (or SARS-CoV-2) viruses from the ongoing novel coronavirus COVID-19 pandemic
Therapeutics 12 April 2020 Yale Medicine (YNHH) COVID-19 Treatment Guidelines The Yale New Haven Health System [https://www.ynhhs.org/] (YNHH) has released its 'Initial Treatment Algorithm for Hospitalized ADULTS with Non–Severe* COVID-19
Scientific Papers 12 April 2020 SARS-CoV-2 on surfaces & air in hospital wards A dispatch paper in Emerging Infectious Diseases (of CDC) has reported on, ' Aerosol and Surface Distribution of Severe Acute Respiratory Syndrome Coronavirus 2 in
Notice 12 April 2020 CRR5 inhibitor reduced Cytokine Storm in COVID-19 CRR5 (CC chemokine receptor 5) was discovered during the heydays of HIV as a coreceptor required for HIV to gain entry into T cells. CRR5
pre-print 12 April 2020 Chloroquine with Azithromycin may have synergistic effects on QT length, needs caution A pre-print paper (medrxiv) suggests that while, 'short-term hydroxychloroquine treatment is safe, addition of azithromycin may induce heart failure and cardiovascular mortality, potentially due
pre-print 12 April 2020 ACE-inhibitors associated with lower COVID-19 severity Contrary to the initial hypothesis that ACE-inhibitors may increase the risk of severe COVID-19 infection, a small study with a cohort of 205 acute COVID-19
Notice 12 April 2020 Herd immunity - level required to halt the COVID-19 worldwide Letter to the Editor of Journal of Infection [http://www.elsevier.com/locate/jinf] entitled, 'Herd immunity – estimating the level required to halt the
Therapeutics 11 April 2020 Convalescent plasma for COVID-19 treatment - Why and How A peer reviewed article [https://onlinelibrary.wiley.com/doi/abs/10.1111/vox.12926] discusses the use of convalescent plasma, i.e. passive polyclonal antibody
Therapeutics 11 April 2020 COVID-19 Critical Care Protocol Eastern Virginia Medical School has released a COVID-19 Critical Care Management Protocol suggesting approaches to prophylaxis and treatment of COVID-19 based on emerging evidences that
Scientific Papers 9 April 2020 Loss of Smell and Taste is a strong indicator or COVID-19 infection Two papers (one non-peer reviewed, preprint) have reported that loss of smell (olfactory) and taste are a significant indication of COVID-19 infection. A peer reviewed
News and Reports 8 April 2020 Emergent Literature on Sterlisation of N95 Masks A University of Manitoba, Canada study advocates Autoclaving of N95 Masks as an accessible method for sterlisation of N95 masks for up to 10 cycles.
Scientific Papers 7 April 2020 Possible Faecal-Oral transmission of SARS-CoV-2 A study from China attests to the Prolonged presence of SARS-CoV-2 viral RNA in faecal samples [https://www.thelancet.com/journals/langas/article/PIIS2468-1253(20)
Scientific Papers 7 April 2020 Cloth Masks need to be used with Caution - 2015 Study 'A cluster randomised trial of cloth masks compared with medical masks in healthcare workers [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420971/]'
Scientific Papers 7 April 2020 EIDD-2801, a NHC prodrug inhibits SARS-CoV-2 in cell cultures and mice A paper published in Science Translational Medicine, reports that, 'prophylactic and therapeutic administration of EIDD-2801, an orally bioavailable NHC-prodrug (β-D-N4-hydroxycytidine-5′-isopropyl ester) - a
Scientific Papers 7 April 2020 Higher climate temperature associated with lower COVID-19 incidence A non-peer reviewed pre-print paper attempts to provide data to support the ongoing theory that increased temperature reduced transmission of SARS-CoV-2, although there has been
